Possibilities of treating prostate cancer

In order to prevent prostate cancer scientists are trying to find abnormal genes that are related to this disease and so identify those who are at risk of developing prostate cancer.
For these people special treatment will be instituted earlier in order to stop the disease from occurring.

Nowadays the scientists use the DNA micro-array technology for studying many genes at the same time and discover those that are related to prostate cancer. This screening could save a lot of time and could replace the currently used PSA blood test.

DNA micro-array identified a product of one gene (named EZH2) that seems to appear more frequently in advanced prostate cancers than in early staged cancers. Scientists want to find out if this gene product signalizes that the cancer is more aggressive or not. This could help doctors decide whether that form of cancer needs treatment or must only be supervised carefully.

Researchers have discovered that tomato and soybeans contain some substances that are useful in preventing prostate cancer (lycopenes and isoflavones). Vitamins are also useful: vitamin D, E and selenium decrease the risk of prostate cancer.

A new clinical trial has been developed in order to see if patients with prostate cancer respond to medication that decreases the level of the androgen hormone called DHT. These drugs (Finasteride and dutasteride) have been used until now only for treating benign prostatic hyperplasia (BPH).

Staging prostate cancer is very important for doctors because it helps them institute the most proper treatment. CT and MRI are not so efficient in this case. Instead, enhanced MRI is quite helpful because it detects the possible cancer cells in the lymph nodes.

As a possibility of treatment is surgery. The radical prostatectomy could have some risks. If the nerves that control erection have to be removed the man will end up being impotent. Doctors are testing a replacement of those nerves with the Sural nerve but they are not positive about the usefulness of this technique.

Radiation therapy is also possible. If using conformal radiation therapy (CRT) and intensity modulated radiation therapy (IMRT) the radiation will be directed straight to the prostate gland and affect less other normal tissues.

Chemotherapy seems to be effective in prostate cancer too. Chemotherapy drugs can be successfully used in combination with other drugs like: Taxotere associated with Calcitriol, a form of vitamin D.

A vaccine has also been tested with amazing results on prostate cancer patients. This vaccine is not like the others that are designed to prevent a disease. This is made to treat advanced prostate cancer by increasing the immune system’s response to cancer cells. The vaccine has been made out of a genetically engineered protein and a dendritic cell provided from the patient’s bloodstream. Three shots of the vaccine (Provenge) were made over the course of a month. The immune system will react and will activate immune T-cells to find and destroy the cancer cells.

Monoclonal antibody treatment can also be applied in this case. They stimulate the body’s natural cell-killing mechanism or they carry a radioactive molecule that will destroy the cancerous cell.

Another treatment is using angiogenesis inhibitors. These drugs prevent the growth of blood vessels and so, the tumor cells will not be nourished any more.

Sometimes the prostate cancer spreads in the body and affects the bones. For stopping the bone pain doctors use radiofrequency ablation (RFA) and CT. with this technique they will destroy the tumor by heating it.

For recovering patients are advised to adopt a certain lifestyle. They must not eat meat, fish, eggs, or dairy products, keep an active lifestyle and even perform yoga.

About Author: For more information about prostate cancer prevention and about early symptoms prostate cancer please review this web site http://www.prostate-cancer-center.com

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The Key Facts Behind Prostate Cancer

Prostate cancer is the most commonly diagnosed cancer of UK men. If it is found early and is still confined to the gland itself then the chances of survival are excellent. Modern surgical techniques, combined with drugs such as Viagra, mean that an operation to treat prostate cancer does not signal the end of a patient's sex-life. The prostate itself is a small, walnut-sized gland situated near the bladder in men that produces one component of semen. There are a broad range of prostate cancers, some of which are extremely gentle and indolent and may not cause any significant ill health. However, others have the ability to spread to other parts of the body and cause more significant damage if not treated. This means it is important to catch prostate cancer early and then it is possible to treat it using a radiotherapy and surgery. The Symptoms of Prostate Cancer The first sign of prostate cancer can be noticed when you go to the toilet. You may find that you are going to the toilet a lot more and that you are unable to maintain a full stream whilst urinating. However, these problems are also associated with a number of medical problems and do not always signal prostate cancer. The symptoms of prostate cancer are caused by the growth of cells, whether malignant or benign, pushing against the urethra, the thin tube which links the bladder to the penis. If you are suffering from the above symptoms then you should also look out for painful urination or ejaculation, blood in urine or semen, and pain in lower back, hips or thighs. Again these symptoms could be caused by any number of things, including infection, but it would be wise to visit your GP to get them checked out. There are several ways that a doctor can check for prostate cancer. The simplest way is the digital rectal examination, in which the doctor insert a gloved finger into the rectum to feel for an an enlarged prostate. Following this a blood test can be conducted to look for any rises in any chemicals in the blood, and after this comes more sophisticated tests, such as ultrasound scans, and x-rays. The Causes of Prostate Cancer The exact causes of prostate cancer are still unclear but there are a number of factors which may increase your chances of developing it. These include, but are not limited to, a family history of prostate cancer, and a fat-rich diet. There have been a number of studies into the link between prostate cancer and vasectomy but these have so far proved to be inconclusive. Treatment for Prostate Cancer Sometimes the best treatment for prostate cancer can be to not treat it at all. This is sometimes the case of older men when it is judged that surgery or other treatments may cause more harm than good. If the cancer has spread from the prostate, or it is believed that it will spread, then surgery is normally the first course of action to remove it whilst is still possible and prevent further spreading. A prostatectomy is when the prostate gland is removed, usually along with small parts of the lymphatic system near the gland. However, this type of surgery can cause nerve damage which can prevent men from getting an erection ever again, or maintain complete control over urination. This does not mean that a man's sex life is over though as modern 'nerve-sparing' surgical techniques, when combined with drugs such as Viagra, can ensure that the effects on both function and quality of life are minimised. Other treatment option is radiotherapy which will be precisely targeted on the pelvic area, whilst other doctors are fighting prostate cancer by using the body's own hormones. In the latter's case, prostate cells, including cancerous ones, which are sensitive to levels of certain male hormones, can be rendered far less active if levels are reduced. However, this can reduce the sex-drive of the patient. Advances in Prostate Cancer Surgery Advances in prostate cancer surgery mean that surgeons can now successfully remove the prostate without causing the problematic nerve damage which has been inevitable in the past. In addition, radiotherapy technology advances mean that far higher doses can be targeted more precisely on the prostate, killing more cancer cells with fewer treatments. A technique called prostate brachytherapy has also made some great advances in recent times and its use is becoming more and more common. There are two methods of brachytherapy - permanent seed implantation and high dose rate (HDR) temporary brachytherapy. Permanent seed implantation involves injecting approximately 100 radioactive seeds into the prostate gland, which give off cancer-killing radiation at a low dose rate over several weeks or months, and the seeds remain in the prostate gland permanently. HDR temporary brachytherapy involves placing very tiny plastic catheters into the prostate gland, and then giving a series of radiation treatments through these catheters. Another option is High Intensity Focussed Ultrasound, which uses sound waves to 'melt' away the cancer.

About Author: The Prostate Cancers Website offers information and resources about prostate cancer. It has details of its causes, symptoms and treatments. For more information please visit http://www.prostate-cancers.co.uk/.

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